Genomic imprinting as an adaptative model of developmental plasticity

The impact of genomic imprinting for neurobehavioral and developmental disorders.

Rex1/Zfp42 as an epigenetic regulator for genomic imprinting.

Zfp42/Rex1 (reduced expression gene 1) is a well-known stem-cell marker that has been duplicated from YY1 in the eutherian lineage. In the current study, we characterized the in vivo roles of Rex1 using a mutant mouse line disrupting its transcription. In contrast to the ubiquitous expression of YY1, Rex1 is expressed only during spermatogenesis and early embryogenesis and also in a very limite...

an examination of developmental dyslexia among iranian efl second graders

چکیده رساله/پایان نامه: این تحقیق جهت بررسی تاثیر نارسا خوانی در یادگیری زبان انگلیسی به عنوان زبان خارجه در میان دانش اموزان ایرانی مقطع دوم راهنمایی طراحی شده است. ده نفر از دانش اموزان ایرانی مقطع دوم راهنمایی و ده نفر از دانش اموزان غیر نارسا خوان همان مقطع برای انجام این تحقیق انتخاب شدند. تمام شرکت کنندگان توسط ازمون زبان انگلیسی ای که برای این هدف ساخته شده و متشکل از بخشهای خواندن ام...

Bayesian inference for genomic imprinting underlying developmental characteristics

The identification of imprinted genes is becoming a standard procedure in searching for quantitative trait loci (QTL) underlying complex traits. When a developmental characteristic such as growth or drug response is observed at multiple time points, understanding the dynamics of gene function governing the underlying feature should provide more biological information regarding the genetic contr...

Genomic Imprinting

BACKGROUND Genomic imprinting is the inheritance out of Mendelian borders. Many of inherited diseases and human development violates Mendelian law of inheritance, this way of inheriting is studied by epigenetics. AIM The aim of this review is to analyze current opinions and options regarding to this way of inheriting. RESULTS Epigenetics shows that gene expression undergoes changes more com...